Portfolio Optimization Model

Vaccines Portfolio Model

Research question: which interventions should be acquired nexts amongst the selection of other competing interventions ? This complex eModel aims to address the question of prioritisation and sequence of introduction. Multi Cohort markov model projects clinical and economic outcomes for a chosen portfolio of interventions. Optimisation sub-model layer maximises an outcome of interest subject to a budgetary and other constraints. Multi Criteria Decision Analysis (MCDA) is applied to define the outcome measure of interest

Links to publications:
http://www.valueinhealthjournal.com/article/S1098-3015(11)02656-8/fulltext
http://www.valueinhealthjournal.com/article/S1098-3015(12)03346-3/fulltext
http://www.valueinhealthjournal.com/article/S1098-3015(13)03684-X/fulltext

Open Model

Vaccines choice
Vaccine Efficacy
Demographics
Epidemiology
Opimisation module
Burden of disease